GABP- beta 1/2 Antibody E-7 è un monoclonale di topo IgG2a κ, citato in 5 pubblicazioni, fornito in 200 µg/ml
generato contro gli amminoacidi 131-395 mappati al C-terminus di GABP-β1 di origine human
GABP- beta 1/2 Antibody (E-7) é raccomandato per il rilevamento di GABP-β1 and GABP-β2 di origine human in WB, IP, IF e ELISA
GABP- beta 1/2 Antibody (E-7) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
reagente TransCruz per utilizzo in ChIP (sc-271571 X, 200 µg/0.1 ml)
Contattaci per ricevere un FREE 10 µg sample di GABP-β1/2 (E-7): sc-271571.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for GABP-β1/2 Antibody (E-7) for WB applications. These reagents are now offered in bundles with GABP-β1/2 Antibody (E-7) (see ordering information below).
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The transcription factor GA-binding protein (GABP) is composed of two subunits, the Ets-related GABP-α and a GABP-α-associated subunit, GABPβ. GABPα binds to a specific DNA sequence and GABPβ exists as b1 and b2 splice variants that differ in their C-termini. In primary neuronal cultures, GABPβ is expressed in both the cytoplasm and the nucleus, whereas GABPα is expressed mainly in the nucleus. GABP is constitutively expressed as either a GABPαβ heterodimer or a GABPαb heterotetramer, both of which can modify GABP-dependent transcription in vitro and in vivo. The GABPαβ tetrameric complex performs many different functions, such as stimulating transcription of the adenovirus E4 gene, differentially activating BRCA1 expression in human breast cell lines, potentiating Tat-mediated activation of long terminal repeat promoter transcription and viral replication in certain cell types, acting as a coordinator of mitochrondrial and nuclear transcription for cytochrome oxidase in neurons and assisting in the regulation of rpL32 gene transcription.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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