FOXQ1 Antibody (B-4): sc-166266
- FOXQ1 Antibody (B-4) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 176-202 within an internal region of FOXQ1 of human origin
- recommended for detection of FOXQ1 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-166266 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FOXQ1 Antibody (B-4) for WB applications. These reagents are now offered in bundles with FOXQ1 Antibody (B-4) (see ordering information below).
FOXQ1 Antibody (B-4) is a mouse monoclonal IgG2a antibody that detects FOXQ1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FOXQ1 plays a crucial role in various biological processes, particularly in the regulation of gene expression during embryogenesis and in specific adult tissues, including the stomach, trachea, bladder, and salivary gland. FOXQ1 is involved in the development of lymphocytes, as evidenced by the phenotypic characteristics of satin homozygous mice, which exhibit defects in hair shaft differentiation and compromised immune function. Notably, FOXQ1 is overexpressed in colorectal adenocarcinoma and lung carcinoma cell lines, highlighting its potential role in cancer progression. FOXQ1′s structure, characterized by a winged-helix or forkhead domain, is essential for DNA-binding capabilities, allowing regulation of target genes critical for development and cellular function. Anti-FOXQ1 antibody (B-4) is an invaluable tool for researchers investigating the intricate roles of FOXQ1 in development, cancer, and immune response.
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FOXQ1 Antibody (B-4) References:
- The Forkhead factor FoxQ1 influences epithelial differentiation. | Feuerborn, A., et al. 2011. J Cell Physiol. 226: 710-9. PMID: 20717954
- FoxQ1 promotes glioma cells proliferation and migration by regulating NRXN3 expression. | Sun, HT., et al. 2013. PLoS One. 8: e55693. PMID: 23383267
- Effects of lentiviral-mediated Foxp1 and Foxq1 RNAi on the hepatocarcinoma cell. | Qin, J., et al. 2014. Exp Mol Pathol. 96: 1-8. PMID: 24211718
- FoxQ1 is a Novel Molecular Target for Pancreatic Cancer and is Associated with Poor Prognosis. | Zhan, HX., et al. 2015. Curr Mol Med. 15: 469-77. PMID: 26122655
- Melanoma Suppressor Functions of the Carcinoma Oncogene FOXQ1. | Bagati, A., et al. 2017. Cell Rep. 20: 2820-2832. PMID: 28930679
- FOXQ1 controls the induced differentiation of melanocytic cells. | Bagati, A., et al. 2018. Cell Death Differ. 25: 1040-1049. PMID: 29463842
- Reciprocal transrepression between FOXF2 and FOXQ1 controls basal-like breast cancer aggressiveness. | Kang, LJ., et al. 2019. FASEB J. 33: 6564-6573. PMID: 30807702
- FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2. | Xiang, L., et al. 2020. Stem Cell Res Ther. 11: 403. PMID: 32943107
- miR-140-3p inhibits bladder cancer cell proliferation and invasion by targeting FOXQ1. | Wang, Y., et al. 2020. Aging (Albany NY). 12: 20366-20379. PMID: 33098639
- Nuclear isoform of RAPH1 interacts with FOXQ1 to promote aggressiveness and radioresistance in breast cancer. | Liu, Q., et al. 2023. Cell Death Dis. 14: 803. PMID: 38062011
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FOXQ1 Antibody (B-4) | sc-166266 | 200 µg/ml | $322.00 | |||
FOXQ1 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-537468 | 200 µg Ab; 10 µg BP | $361.00 | |||
FOXQ1 Antibody (B-4): m-IgGκ BP-HRP Bundle | sc-534744 | 200 µg Ab; 40 µg BP | $361.00 | |||
FOXQ1 Antibody (B-4): m-IgG2a BP-HRP Bundle | sc-548024 | 200 µg Ab; 10 µg BP | $361.00 | |||
FOXQ1 (B-4) Neutralizing Peptide | sc-166266 P | 100 µg/0.5 ml | $69.00 | |||
FOXQ1 Antibody (B-4) X | sc-166266 X | 200 µg/0.1 ml | $322.00 |