Fibronectin Antibody (568): sc-52331
- Fibronectin Antibody (568) is a mouse monoclonal IgG1 κ, cited in 27 publications, provided at 200 µg/ml
- raised against isolated cultured fibroblasts of human origin
- Anti-Fibronectin Antibody (568) is recommended for detection of Fibronectin of mouse, rat and human origin by WB, IP, IF and IHC(P)
- Anti-Fibronectin Antibody (568) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Fibronectin Antibody (568) for WB and IHC(P) applications. These reagents are now offered in bundles with Fibronectin Antibody (568) (see ordering information below).
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Fibronectin Antibody (568) is a mouse monoclonal IgG1 kappa light chain antibody that detects Fibronectin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Fibronectin antibody (568) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Fibronectin is a crucial extracellular matrix glycoprotein that plays a significant role in cell adhesion, motility, and wound healing, making Fibronectin essential for tissue repair and regeneration. This high molecular weight heterodimeric protein is predominantly located in the extracellular matrix, where Fibronectin facilitates the interaction between cells and their environment, thereby influencing cellular behavior and tissue architecture. Alternative splicing and glycosylation of Fibronectin lead to the generation of various isoforms, some of which are associated with specific tissues or pathological conditions, such as malignancies. The presence of glycosylated Fibronectin and splice variants has been linked to the myofibroblast phenotype in Dupuytren′s disease, highlighting the importance of understanding Fibronectin′s structural diversity and functional implications in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Fibronectin Antibody (568) References:
- Fibronectin requirement in branching morphogenesis. | Sakai, T., et al. 2003. Nature. 423: 876-81. PMID: 12815434
- Mechanisms of fibronectin and integrin function during cell adhesion and migration. | Yamada, KM., et al. 1992. Cold Spring Harb Symp Quant Biol. 57: 203-12. PMID: 1339659
- Fibronectin as target for tumor therapy. | Kaspar, M., et al. 2006. Int J Cancer. 118: 1331-9. PMID: 16381025
- Therapeutic administration of fibronectin: current uses and potential applications. | Yoder, MC. 1991. Clin Perinatol. 18: 325-41. PMID: 1879111
- Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins. | Henderson, B., et al. 2011. FEMS Microbiol Rev. 35: 147-200. PMID: 20695902
- Fibronectin matrix deposition and fibronectin receptor expression in healing and normal skin. | Clark, RA. 1990. J Invest Dermatol. 94: 128S-134S. PMID: 2161886
- Cell migration on material-driven fibronectin microenvironments. | Grigoriou, E., et al. 2017. Biomater Sci. 5: 1326-1333. PMID: 28612879
- Purification of Human Plasma/Cellular Fibronectin and Fibronectin Fragments. | Pietrocola, G., et al. 2017. Methods Mol Biol. 1627: 309-324. PMID: 28836210
- Fibronectin and integrins in invasion and metastasis. | Akiyama, SK., et al. 1995. Cancer Metastasis Rev. 14: 173-89. PMID: 8548867
- Fibronectin regulates calvarial osteoblast differentiation. | Moursi, AM., et al. 1996. J Cell Sci. 109 (Pt 6): 1369-80. PMID: 8799825
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibronectin Antibody (568) | sc-52331 | 200 µg/ml | $322.00 | |||
Fibronectin Antibody (568): m-IgG Fc BP-HRP Bundle | sc-526754 | 200 µg Ab; 10 µg BP | $361.00 | |||
Fibronectin Antibody (568): m-IgG1 BP-HRP Bundle | sc-532127 | 200 µg Ab; 20 µg BP | $361.00 | |||
Fibronectin Antibody (568) AC | sc-52331 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Fibronectin Antibody (568) HRP | sc-52331 HRP | 200 µg/ml | $322.00 | |||
Fibronectin Antibody (568) FITC | sc-52331 FITC | 200 µg/ml | $336.00 | |||
Fibronectin Antibody (568) PE | sc-52331 PE | 200 µg/ml | $349.00 | |||
Fibronectin Antibody (568) Alexa Fluor® 488 | sc-52331 AF488 | 200 µg/ml | $364.00 | |||
Fibronectin Antibody (568) Alexa Fluor® 546 | sc-52331 AF546 | 200 µg/ml | $364.00 | |||
Fibronectin Antibody (568) Alexa Fluor® 594 | sc-52331 AF594 | 200 µg/ml | $364.00 | |||
Fibronectin Antibody (568) Alexa Fluor® 647 | sc-52331 AF647 | 200 µg/ml | $364.00 | |||
Fibronectin Antibody (568) Alexa Fluor® 680 | sc-52331 AF680 | 200 µg/ml | $364.00 | |||
Fibronectin Antibody (568) Alexa Fluor® 790 | sc-52331 AF790 | 200 µg/ml | $364.00 |