Ep-CAM Antibody (3H2141): sc-71056
- Ep-CAM Antibody (3H2141) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against HT29 carcinoma cell line of human origin
- recommended for detection of Ep-CAM of human origin by WB, IP, IF and IHC(P)
- See Ep-CAM (C-10): sc-25308 for Ep-CAM antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Ep-CAM Antibody (3H2141) for WB and IHC(P) applications. These reagents are now offered in bundles with Ep-CAM Antibody (3H2141) (see ordering information below).
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SEE ALSO...
Ep-CAM Antibody (3H2141) is a mouse monoclonal IgG1 antibody that detects Ep-CAM in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Ep-CAM, also known as tumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein predominantly expressed in normal human epithelial tissues and various carcinomas, making Ep-CAM a significant marker for cancer research. The human Ep-CAM gene encodes a 314 amino acid protein that exists in two forms, with the major form being more prevalent and the minor form being reduced upon treatment with the amino-glycosylation inhibitor tunicamycin. Notably, Ep-CAM is characterized by an extracellular domain, which contains two epidermal growth factor-like repeats followed by a cysteine-poor region; this unique structure is crucial for adhesion properties, facilitating cell-cell interactions that are vital for maintaining tissue integrity. Given Ep-CAM′s overexpression in numerous carcinomas, anti-Ep-CAM antibody (3H2141) serves as a promising tool for both visualization and therapeutic intervention of human solid tumors, underscoring Ep-CAM′s importance in cancer diagnostics and treatment strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ep-CAM Antibody (3H2141) | sc-71056 | 200 µg/ml | $322.00 | |||
Ep-CAM Antibody (3H2141): m-IgG Fc BP-HRP Bundle | sc-539339 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ep-CAM Antibody (3H2141): m-IgG1 BP-HRP Bundle | sc-541422 | 200 µg Ab; 20 µg BP | $361.00 |