EBV viral capsid antigen Antibody (0231): sc-58122

EBV viral capsid antigen Antibody (0231) is a mouse monoclonal IgG1 antibody that detects the EBV viral capsid antigen protein of EBV origin by immunofluorescence (IF). Anti-EBV viral capsid antigen antibody (0231) is available as the non-conjugated format. The Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a member of the herpesvirus family and is one of the most prevalent human viruses, infecting approximately 90% of the global population. EBV specifically targets B lymphocytes, and while many infections remain asymptomatic, EBV can lead to infectious mononucleosis, which presents with symptoms such as fatigue, fever, sore throat, and muscle aches. The viral capsid antigen (VCA) plays a crucial role in the virus′s life cycle and is essential for the initial stages of infection, as VCA facilitates the attachment and entry of the virus into host cells. Understanding VCA function is vital, as VCA not only serves as a marker for diagnosing EBV infections but also has implications in the development of associated malignancies, including Burkitt lymphoma and nasopharyngeal carcinoma. VCA is frequently utilized in diagnostic tests, making EBV viral capsid antigen (0231) monoclonal antibody an invaluable tool for researchers and clinicians studying EBV-related diseases.

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EBV viral capsid antigen Antibody (0231) References:

1. Epstein-barr virus regulates c-MYC, apoptosis, and tumorigenicity in Burkitt lymphoma.  |  Ruf, IK., et al. 1999. Mol Cell Biol. 19: 1651-60. PMID: 10022853
2. Specific IgA antibody to Epstein-Barr viral capsid antigen: a better marker for screening nasopharyngeal carcinoma than EBV-DNA detection by polymerase chain reaction.  |  Kantakamalakul, W., et al. 2000. Asian Pac J Allergy Immunol. 18: 221-6. PMID: 11316043
3. Epstein-Barr Viral Antigens Used in the Diagnosis of Nasopharyngeal Carcinoma.  |  Gan, YY., et al. 1996. J Biomed Sci. 3: 159-169. PMID: 11725096
4. Cell target genes of Epstein-Barr virus transcription factor EBNA-2: induction of the p55alpha regulatory subunit of PI3-kinase and its role in survival of EREB2.5 cells.  |  Spender, LC., et al. 2006. J Gen Virol. 87: 2859-2867. PMID: 16963743
5. Serodiagnosis of infectious mononucleosis by using recombinant Epstein-Barr virus antigens and enzyme-linked immunosorbent assay technology.  |  Gorgievski-Hrisoho, M., et al. 1990. J Clin Microbiol. 28: 2305-11. PMID: 2172287
6. Characterization of the restricted component of Epstein-Barr virus early antigens as a cytoplasmic filamentous protein.  |  Luka, J., et al. 1986. J Virol. 58: 748-56. PMID: 2422401
7. Neutralization of Epstein-Barr virus-induced ribonucleotide reductase with antibody to the major restricted early antigen polypeptide.  |  Goldschmidts, WL., et al. 1989. Virology. 170: 330-3. PMID: 2541553
8. [Expression of the Epstein-Barr virus P150 viral capsid antigen in Escherichia coli for the use as antigen in diagnostic tests].  |  Fan, JA. 1989. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 11: 381-7. PMID: 2561513
9. Detection of human antibodies using 'convergent' combinatorial peptide libraries or 'mixotopes' designed from a nonvariable antigen: application to the EBV viral capsid antigen p18.  |  Tranchand-Bunel, D., et al. 1998. J Pept Res. 52: 495-508. PMID: 9924994

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-EBV viral capsid antigen Antibody (0231) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

EBV viral capsid antigen Antibody (0231) Specifications

Alternate Product Name: EBV viral capsid antigen

Product Clone Name: 0231

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: EBV viral capsid antigen

Epitope Species: EBV

Product Reactivity/Detection: EBV viral capsid antigen

Species Reactivity/Detection: EBV

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for EBV viral capsid antigen Antibody (0231): N/A