Cyanine 5-UTP
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Cyanine 5-UTP(Cy5-UTP) acts as a substrate for T7 RNA polymerase, enabling the production of labeled probes through in vitro transcription. These synthesized mRNA molecules exhibit vibrant orange fluorescence attributed to the incorporation of Cyanine 5-UTP. Moreover, the Cy5-labeled mRNA probes are easily detectable under ultraviolet light without the need for additional staining after gel electrophoresis. Such probes, created using these techniques, find applications including Fluorescence In Situ Hybridization (FISH), multicolor fluorescence analysis, and dual-color expression arrays, when used in combination with Cyanine 5-UTP. The excitation and emission wavelengths for Cyanine 5-UTPare 650 nm and 665 nm, respectively.
Cyanine 5-UTP References
- Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles. | Wu, Y., et al. 2004. Nucleic Acids Res. 32: e123. PMID: 15333674
- OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/- mice aortas. | Reeve, JL., et al. 2007. Biochem Biophys Res Commun. 356: 681-6. PMID: 17374365
- Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus. | Hutchinson, EC., et al. 2008. J Virol. 82: 11869-79. PMID: 18815307
- A Rab11- and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA. | Amorim, MJ., et al. 2011. J Virol. 85: 4143-56. PMID: 21307188
- Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28. | Smargon, AA., et al. 2017. Mol Cell. 65: 618-630.e7. PMID: 28065598
- Delivery of mRNA to platelets using lipid nanoparticles. | Novakowski, S., et al. 2019. Sci Rep. 9: 552. PMID: 30679556
- Size-Controllable Enzymatic Synthesis of Short Hairpin RNA Nanoparticles by Controlling the Rate of RNA Polymerization. | Kim, H., et al. 2018. Polymers (Basel). 10: PMID: 30966623
- Modulation of RNA Condensation by the DEAD-Box Protein eIF4A. | Tauber, D., et al. 2020. Cell. 180: 411-426.e16. PMID: 31928844
- An In Vitro Assembly System Identifies Roles for RNA Nucleation and ATP in Yeast Stress Granule Formation. | Begovich, K. and Wilhelm, JE. 2020. Mol Cell. 79: 991-1007.e4. PMID: 32780990
- mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells. | Bevers, S., et al. 2022. Mol Ther. 30: 3078-3094. PMID: 35821637
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyanine 5-UTP, 250 nmol | sc-499469 | 250 nmol | $436.00 |