COPB Antibody (C-11): sc-137226
- COPB Antibody (C-11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 654-953 mapping at the C-terminus of COPB of human origin
- recommended for detection of COPB of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG1 BP-HRP is the preferred secondary detection reagent for COPB Antibody (C-11) for WB applications. This reagent is now offered in a bundle with COPB Antibody (C-11) (see ordering information below).
COPB Antibody (C-11) is a mouse monoclonal IgG1 antibody that detects COPB in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COPB, also known as β-COP, plays a crucial role in membrane and vesicular trafficking within the early secretory pathway, specifically as a marker protein for pre-Golgi intermediates, including vesicular tubular clusters (VTCs). COPB functions as a major component of the coat of non-Clathrin-coated vesicles, which are essential for mediating membrane traffic through the Golgi complex. This trafficking is vital for proper sorting and delivery of proteins and lipids, ensuring cellular processes function efficiently. Additionally, COPB interacts with various proteins, including GIV (Gα i/s interacting protein) and β′-COP (COPP), which co-localize with COPB at critical sites such as the endoplasmic reticulum exit sites and the Golgi complex. COPB′s ability to form complexes with these proteins highlights COPB′s significance in maintaining cellular organization and facilitating communication between different cellular compartments. anti-COPB antibody (C-11) serves as an invaluable tool for researchers studying the dynamics of vesicular transport and protein sorting in cellular biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COPB Antibody (C-11) | sc-137226 | 200 µg/ml | $322.00 | |||
COPB Antibody (C-11): m-IgG1 BP-HRP Bundle | sc-542652 | 200 µg Ab; 20 µg BP | $361.00 |