Anti-CBP/KAT3A/CREBBP Antibody C-1 è un monoclonale di topo IgG1 κ CBP/KAT3A/CREBBP antibody, citato in 130 pubblicazioni, fornito in 200 µg/ml
specific for an epitope mapping between amino acids 2423-2442 at the C-terminus of CBP of human origin (identical to corresponding mouse sequence)
CBP/KAT3A/CREBBP Antibody (C-1) é raccomandato per il rilevamento di CBP p265 di origine mouse, rat, human e in WB, IP, IF, IHC(P) and ELISA; anche reattivo con ulteriori specie, incluse e canine, bovine, porcine and avian
CBP/KAT3A/CREBBP Antibody (C-1) é disponibile coniugato con agarose per IP; HRP per WB, IHC(P) ed ELISA; sia con phycoerythrin o FITC per IF, IHC(P) e FCM
disponibile anche coniugato con Alexa Fluor® 488, Alexa Fluor® 546; Alexa Fluor® 594 o Alexa Fluor® 647 per IF, IHC (P) e FCM
disponibile anche coniugato con Alexa Fluor® 680 o Alexa Fluor® 790 per WB (NIR), IF e FCM
reagente TransCruz per utilizzo in Gel Supershift e ChIP (sc-7300 X, 200 µg/0.1 ml)
Contattaci per ricevere un FREE 10 µg sample di CBP/KAT3A/CREBBP (C-1): sc-7300.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CBP/KAT3A/CREBBP Antibody (C-1). This work is in progress.
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Labware ships FedEx Ground free of charge to the contiguous US
CBP Antibody (C-1) is a high quality monoclonal CBP antibody (also designated CREBBP antibody or KAT3A antibody) suitable for the detection of the CBP protein of mouse, rat and human origin. CBP Antibody (C-1) is available as both the non-conjugated anti-CBP antibody form, as well as multiple conjugated forms of anti-CBP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB, which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 molecules lacking an intact E1A binding site bypass E1A repression, even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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