Budesonide-d8 (CAS 1105542-94-6)
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Budesonide-d8, a synthetic corticosteroid, has found extensive application in laboratory experiments aimed at investigating the physiological and biochemical impacts of glucocorticoids. This stable derivative of the glucocorticoid offers a non-metabolizable form, eliminating concerns associated with metabolic processes. The mechanism of action of Budesonide-d8 revolves around its interaction with the glucocorticoid receptor, a nuclear receptor present in numerous tissues throughout the body. Binding to the glucocorticoid receptor initiates a cascade of molecular events, resulting in alterations in gene expression and the synthesis of proteins that intricately regulate various physiological processes. Through its selective binding and subsequent downstream effects, Budesonide-d8 serves as useful for investigating the intricate workings of glucocorticoids in cellular and molecular contexts.
Budesonide-d8 (CAS 1105542-94-6) References
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- Pharmacokinetics and Bioequivalence of a Generic and a Branded Budesonide Nasal Spray in Healthy Chinese Subjects. | Li, X., et al. 2022. Clin Pharmacol Drug Dev. 11: 516-522. PMID: 34783456
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Budesonide-d8, 1 mg | sc-217797 | 1 mg | $357.00 | |||
Budesonide-d8, 10 mg | sc-217797A | 10 mg | $2501.00 |