apoM Antibody (D-4): sc-398762

ApoM Antibody (D-4) is a mouse monoclonal IgG2b antibody that detects Apolipoprotein M in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ApoM, also known as protein G3a, is a crucial member of the Lipocalin family of proteins, primarily expressed in kidney tubular epithelial cells and liver hepatocytes. anti-ApoM antibody (D-4) plays a significant role in studying reverse cholesterol transport, which is vital for maintaining lipid homeostasis and preventing atherosclerosis. ApoM is known to associate predominantly with high-density lipoprotein (HDL) and is involved in the formation of preβ-HDL, an essential acceptor of peripheral cellular cholesterol. The structural integrity of ApoM, characterized by its eight-stranded antiparallel β-barrel, allows binding to retinol and retinoic acid effectively, further emphasizing its importance in lipid metabolism. Notably, the concentration of ApoM in plasma is strongly correlated with total cholesterol levels, and low plasma concentrations of ApoM have been linked to diabetes, highlighting its potential as a biomarker for metabolic disorders. ApoM monoclonal antibody (D-4) serves as an invaluable tool for researchers studying lipid metabolism and related diseases.

The preferred apoM antibody is apoM Antibody (A-10): sc-365139.