Molecular structure of ACBC, CAS Number: 22264-50-2
ACBC (CAS 22264-50-2)
Alternate Names:
1-Aminocyclobutanecarboxylic acid
Application:
ACBC is an NMDA receptor antagonist that acts at the glycine site
CAS Number:
22264-50-2
Molecular Weight:
115.13
Molecular Formula:
C5H9NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
ACBC is an NMDA receptor antagonist acting at the glycine site.
ACBC (CAS 22264-50-2) References
- Modulation of [3H]3-((+-)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid ([3H]CPP) binding by ligands acting at the glycine and the polyamine sites of the rat brain NMDA receptor complex. | Porter, RH., et al. 1992. Eur J Pharmacol. 227: 83-8. PMID: 1426025
- Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. | Inanobe, A., et al. 2005. Neuron. 47: 71-84. PMID: 15996549
- Effect of structure on tumor specificity of alicyclic alpha-amino acids. | Washburn, LC., et al. 1978. Cancer Res. 38: 2271-3. PMID: 208763
- Neuropharmacological characterization of 1-aminocyclopropane-1-carboxylate and 1-aminocyclobutane-1-carboxylate, ligands of the N-methyl-D-aspartate-associated glycine receptor. | Rao, TS., et al. 1990. Neuropharmacology. 29: 305-9. PMID: 2158004
- 1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor. | Hood, WF., et al. 1989. Eur J Pharmacol. 161: 281-2. PMID: 2542048
- Chemotherapeutic potential of methionine analogue inhibitors of tumor-derived methionine adenosyltransferases. | Lombardini, JB. and Sufrin, JR. 1983. Biochem Pharmacol. 32: 489-95. PMID: 6847699
- Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. | Priestley, T., et al. 1995. Mol Pharmacol. 48: 841-8. PMID: 7476914
- Synthesis, NMDA receptor antagonist activity, and anticonvulsant action of 1-aminocyclobutanecarboxylic acid derivatives. | Gaoni, Y., et al. 1994. J Med Chem. 37: 4288-96. PMID: 7996540
- [3H]1-aminocyclopropanecarboxylic acid, a novel probe for strychnine- insensitive glycine receptors. | Popik, P., et al. 1995. Eur J Pharmacol. 291: 221-7. PMID: 8719405
- 1-Aminocyclobutanecarboxylic acid derivatives as novel structural elements in bioactive peptides: application to tuftsin analogs. | Gershonov, E., et al. 1996. J Med Chem. 39: 4833-43. PMID: 8941397
- Ethylene biosynthesis: processing of a substrate analog supports a radical mechanism for the ethylene-forming enzyme. | Pirrung, MC., et al. 1998. Chem Biol. 5: 49-57. PMID: 9479479
Inhibitor of:
NMDA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACBC, 1 g | sc-203493 | 1 g | $61.00 |