Molecular structure of 5β-Dihydro Progesterone, CAS Number: 128-23-4
5β-Dihydro Progesterone (CAS 128-23-4)
Alternate Names:
Pregnanedione
Application:
5β-Dihydro Progesterone is a metabolite of Progesterone
CAS Number:
128-23-4
Molecular Weight:
316.48
Molecular Formula:
C21H32O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
5 beta-Dihydro Progesterone (5β-DHP) is a neuroactive steroid metabolite derived from Progesterone. It is also known as 5beta-pregnanedione, a steroid hormone that interacts with the GABA-A receptor and the glucocorticoid receptor to elicit its effects. It plays a role in regulating the immune system and is involved in the modulation of the stress response.
5β-Dihydro Progesterone (CAS 128-23-4) References
- Progesterone metabolite and spontaneous myometrial contractions in vitro. | Thornton, S., et al. 1999. Lancet. 353: 1327-9. PMID: 10218536
- Bioactive 5-reduced 16 alpha,17 alpha-cyclohexanoprogesterone derivatives weakly interact with proteins of the soluble uterine fraction. | Smirnov, AN., et al. 2001. Bull Exp Biol Med. 131: 245-7. PMID: 11427910
- Oxytocin inhibits LH-stimulated production of androstenedione by bovine theca cells. | Jo, M. and Fortune, JE. 2002. Mol Cell Endocrinol. 188: 151-9. PMID: 11911954
- The effects of a progesterone metabolite, 5 beta-dihydroprogesterone, on oxytocin receptor binding in human myometrial membranes. | Astle, S., et al. 2003. BJOG. 110: 589-92. PMID: 12798477
- Regulation of myometrial smooth muscle functions. | Hertelendy, F. and Zakar, T. 2004. Curr Pharm Des. 10: 2499-517. PMID: 15320759
- 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term. | Sheehan, PM., et al. 2005. Mol Hum Reprod. 11: 495-501. PMID: 16123077
- Progesterone receptors in the human pregnancy uterus: do they hold the key to birth timing? | Mesiano, S., et al. 2011. Reprod Sci. 18: 6-19. PMID: 20889955
- Maternal Serum Lipid, Estradiol, and Progesterone Levels in Pregnancy, and the Impact of Placental and Hepatic Pathologies. | Pecks, U., et al. 2016. Geburtshilfe Frauenheilkd. 76: 799-808. PMID: 27582578
- Current Perspectives for the use of Gonane Progesteronergic Drugs in the Treatment of Central Hypoventilation Syndromes. | Loiseau, C., et al. 2018. Curr Neuropharmacol. 16: 1433-1454. PMID: 28721821
- Progesterone-Related Immune Modulation of Pregnancy and Labor. | Shah, NM., et al. 2019. Front Endocrinol (Lausanne). 10: 198. PMID: 30984115
- Selective ligands of membrane progesterone receptors as a key to studying their biological functions in vitro and in vivo. | Levina, IS., et al. 2021. J Steroid Biochem Mol Biol. 207: 105827. PMID: 33497793
- Specificity of antibodies to ovarian hormones in relation to the steroid hapten to the peptide carrier. | Lindner, HR., et al. 1972. Steroids. 19: 357-75. PMID: 5028413
- Direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids | Ramachary, D. B., Sakthidevi, R., & Reddy, P. S. 2013. RSC advances. 3(32): 13497-13506.
Activator of:
Na+/K+-ATPase α3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5β-Dihydro Progesterone, 100 mg | sc-210426 | 100 mg | $234.00 |