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3′-Aminoacetophenone (CAS 99-03-6)

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Alternate Names:
3-Acetylaniline
Application:
3′-Aminoacetophenone is acts as bifunctional coupling reagent during the synthesis of pyrimidines
CAS Number:
99-03-6
Molecular Weight:
135.16
Molecular Formula:
C8H9NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3′-Aminoacetophenone acts as bifunctional coupling reagent during the synthesis of pyrimidines. 3′-Aminoacetophenone (3-Acetylaniline) was used as reagent during the asymmetric total synthesis of pactamycin. It was used as starting reagent during the synthesis of curcumin mimics with substituted sulfonyl group.


3′-Aminoacetophenone (CAS 99-03-6) References

  1. Symmetric building blocks and combinatorial functional group transformation as versatile strategies in combinatorial chemistry.  |  Früchtel, JS., et al. Biotechnol Bioeng. 71: 94-103. PMID: 11288063
  2. Cloning of the pactamycin biosynthetic gene cluster and characterization of a crucial glycosyltransferase prior to a unique cyclopentane ring formation.  |  Kudo, F., et al. 2007. J Antibiot (Tokyo). 60: 492-503. PMID: 17827660
  3. FT-IR, NIR-FT-Raman and gas phase infrared spectra of 3-aminoacetophenone by density functional theory and ab initio Hartree-Fock calculations.  |  Subramanian, MK., et al. 2008. Spectrochim Acta A Mol Biomol Spectrosc. 71: 59-67. PMID: 18178129
  4. Synthesis and antioxidant, cytotoxicity and antimicrobial activities of novel curcumin mimics.  |  Bandgar, BP., et al. 2012. J Enzyme Inhib Med Chem. 27: 267-74. PMID: 21679049
  5. Synthesis, biological evaluation, and molecular docking of N-{3-[3-(9-methyl-9H-carbazol-3-yl)-acryloyl]-phenyl}-benzamide/amide derivatives as xanthine oxidase and tyrosinase inhibitors.  |  Bandgar, BP., et al. 2012. Bioorg Med Chem. 20: 5649-57. PMID: 22901670
  6. Functional Characterization of 3-Aminobenzoic Acid Adenylation Enzyme PctU and UDP-N-Acetyl-d-Glucosamine: 3-Aminobenzoyl-ACP Glycosyltransferase PctL in Pactamycin Biosynthesis.  |  Kudo, F., et al. 2019. Chembiochem. 20: 2458-2462. PMID: 31059166
  7. Glycosylation of acyl carrier protein-bound polyketides during pactamycin biosynthesis.  |  Eida, AA., et al. 2019. Nat Chem Biol. 15: 795-802. PMID: 31308531
  8. EGFR and COX-2 Dual Inhibitor: The Design, Synthesis, and Biological Evaluation of Novel Chalcones.  |  Musa, A., et al. 2022. Molecules. 27: PMID: 35208952

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3′-Aminoacetophenone, 25 g

sc-238715
25 g
$50.00