Date published: 2026-4-25

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2-Nitroethanol (CAS 625-48-9)

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CAS Number:
625-48-9
Purity:
≥95%
Molecular Weight:
91.07
Molecular Formula:
C2H5NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Nitroethanol is a notable chemical compound characterized by the presence of both nitro and hydroxyl functional groups attached to an ethane backbone. It is used in various research settings due to its reactivity and ability to participate in diverse chemical reactions. This compound acts as an effective intermediate in organic synthesis, facilitating the production of more complex molecules through nitroaldol reactions. Its dual functionality allows for modifications under different chemical conditions, making it useful for the synthesis of nitro-containing organic compounds. Researchers value 2-nitroethanol for its versatility and efficacy in promoting specific reaction pathways, which are critical in the development of novel materials and chemicals. The presence of the nitro group adjacent to the hydroxyl group significantly alters the electronic environment of the molecule, influencing its reactivity and interactions with other chemical entities.


2-Nitroethanol (CAS 625-48-9) References

  1. The nitromethane and 2-nitroethanol synthesis.  |  SOWDEN, JC. 1951. Adv Carbohydr Chem. 6: 291-318. PMID: 14894355
  2. Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro.  |  Horrocks, SM., et al. 2007. J Food Sci. 72: M50-5. PMID: 17995842
  3. Aliphatic beta-nitro alcohols for non-enzymatic collagen cross-linking of scleral tissue.  |  Paik, DC., et al. 2008. Exp Eye Res. 87: 279-85. PMID: 18616942
  4. Short chain aliphatic beta-nitro alcohols for corneoscleral cross-linking: corneal endothelial toxicity studies.  |  Paik, DC., et al. 2008. J Refract Surg. 24: S741-7. PMID: 18811122
  5. Aliphatic beta-nitroalcohols for therapeutic corneoscleral cross-linking: chemical mechanisms and higher order nitroalcohols.  |  Paik, DC., et al. 2010. Invest Ophthalmol Vis Sci. 51: 836-43. PMID: 19797229
  6. Combination effects of nitrocompounds, pyromellitic diimide, and 2-bromoethanesulfonate on in vitro ruminal methane production and fermentation of a grain-rich feed.  |  Zhang, DF. and Yang, HJ. 2012. J Agric Food Chem. 60: 364-71. PMID: 22129139
  7. Polynitroethyl- and fluorodinitroethyl substituted boron esters.  |  Klapötke, TM., et al. 2013. Chemistry. 19: 12113-23. PMID: 23893716
  8. Short chain nitrocompounds as a treatment of layer hen manure and litter; effects on in vitro survivability of Salmonella, generic E. coli and nitrogen metabolism.  |  Ruiz-Barrera, O., et al. 2017. J Environ Sci Health B. 52: 23-29. PMID: 27628961
  9. In Vitro Evaluation of Different Dietary Methane Mitigation Strategies.  |  Chagas, JC., et al. 2019. Animals (Basel). 9: PMID: 31835803
  10. The Antimethanogenic Nitrocompounds Can be Cleaved into Nitrite by Rumen Microorganisms: A Comparison of Nitroethane, 2-Nitroethanol, and 2-Nitro-1-propanol.  |  Zhang, ZW., et al. 2019. Metabolites. 10: PMID: 31881649
  11. Rumen Methanogenesis, Rumen Fermentation, and Microbial Community Response to Nitroethane, 2-Nitroethanol, and 2-Nitro-1-Propanol: An In Vitro Study.  |  Zhang, Z., et al. 2020. Animals (Basel). 10: PMID: 32182983
  12. The Dietary Supplemental Effect of Nitroethanol in Comparison with Monensin on Methane Emission, Growth Performance and Carcass Characteristics in Female Lambs.  |  Zhang, ZW., et al. 2021. Animals (Basel). 11: PMID: 33525565
  13. Astragallus mollissimus plant extract: a strategy to reduce ruminal methanogenesis.  |  Ochoa-García, PA., et al. 2021. Trop Anim Health Prod. 53: 436. PMID: 34401959

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Nitroethanol, 5 g

sc-238175
5 g
$59.00

2-Nitroethanol, 25 g

sc-238175A
25 g
$201.00