Date published: 2026-8-14

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2-Chloro-1H-indole-3-carboxylic acid (CAS 54778-20-0)

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CAS Number:
54778-20-0
Molecular Weight:
195.60
Molecular Formula:
C9H6ClNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloro-1H-indole-3-carboxylic acid, a chlorinated indole derivative, has found extensive utility in various scientific research applications. The scientific research applications of 2-Chloro-1H-indole-3-carboxylic acid encompass a broad spectrum. It serves as a component in the synthesis of indole-3-carboxamides, derivatives of indole-3-carboxylic acid, and analogs of indole-3-carboxylic acid. Additionally, it plays a vital role in the synthesis of other indoles and indole derivatives. The reactivity of 2-Chloro-1H-indole-3-carboxylic acid is attributed to its ability to accept protons in the presence of an appropriate base. This characteristic enables the compound to engage in reactions with other compounds, resulting in the formation of desired products. Specifically, the reaction of 2-Chloro-1H-indole-3-carboxylic acid with a suitable base predominantly yields a carboxylic acid as the major product.


2-Chloro-1H-indole-3-carboxylic acid (CAS 54778-20-0) References

  1. Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1.  |  Zaienne, D., et al. 2021. J Med Chem. 64: 15126-15140. PMID: 34633810
  2. Convenient Chlorination of Some Special Aromatic Compounds Using N-Chlorosuccinimide  |  Zongjie Gan¹, Bin Hu¹, Qiao Song, Yungen Xu*. 2012. Synthesis. (7):: 1074-1078.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloro-1H-indole-3-carboxylic acid, 100 mg

sc-460373
100 mg
$194.00