Molecular structure of 16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester, CAS Number: 62873-55-6
16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester (CAS 62873-55-6)
Application:
16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester is a prodrug for the compound 16,16-dimethyl PGE2
CAS Number:
62873-55-6
Molecular Weight:
632.8
Molecular Formula:
C37H48N2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester is a crystalline prostaglandin derivative believed to act as a prodrug for 16,16-dimethyl PGE2 (sc-201240). 16,16-dimethyl PGE2 is an antisecretory, antiulcer Prostaglandin E2 (PGE2; sc-201225) analog with potent cytoprotective activity that binds to PGDH (prostaglandin dehydrogenase or HPGD), but is resistant to metabolism, thereby inhibiting the enzyme. This enhanced resistance to metabolism imparts a higher duration of activity than Prostaglandin E2 (sc-201225), but the methylations do not severely affect the binding affinity for all four EP receptors (EP1,2,3, and 4).
16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester (CAS 62873-55-6) References
- Gastric antisecretory and antiulcer properties of PGE2, 15-methyl PGE2, and 16, 16-dimethyl PGE2. Intravenous, oral and intrajejunal administration. | Robert, A., et al. 1976. Gastroenterology. 70: 359-70. PMID: 174967
- Studies on 15-hydroxyprostaglandin dehydrogenase with various prostaglandin analogues. | Ohno, H., et al. 1978. J Biochem. 84: 1485-94. PMID: 216666
- 16,16-Dimethyl prostaglandin E2 delays collagen formation in nutritional injury in rat liver. | Ruwart, MJ., et al. 1988. Hepatology. 8: 61-4. PMID: 3338720
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester, 500 µg | sc-205053 | 500 µg | $66.00 | |||
16,16-dimethyl Prostaglandin E2 p-(p-acetamidobenzamido) phenyl ester, 1 mg | sc-205053A | 1 mg | $126.00 |