Molecular structure of 1,10-Phenanthroline-5,6-dione, CAS Number: 27318-90-7
1,10-Phenanthroline-5,6-dione (CAS 27318-90-7)
Application:
1,10-Phenanthroline-5,6-dione is A Bifunctional quinone oxidant
CAS Number:
27318-90-7
Purity:
≥98%
Molecular Weight:
210.19
Molecular Formula:
C12H6N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
1,10-Phenanthroline-5,6-dione is a bifunctional quinone oxidant which, when used in conjunction with Zn2+ catalysts, is used to affect the aerobic oxidation of secondary amines to a variety of value added motifs, including indoles. It is used in the synthesis of dyes, catalysts, and other organic compounds, such as quinones, amides, and lactones. Also, it acts as a chelating agent. Furthermore, 1,10-Phenanthroline-5,6-dione has been used to enhance the solubility of certain compounds, as well as to stabilize proteins and other biomolecules. In addition, it can be utilized to detect the presence of metal ions, and it is used in the synthesis of polymers-based nanomaterials. Finally, it can be employed as an antioxidant to protect against oxidative damage.
1,10-Phenanthroline-5,6-dione (CAS 27318-90-7) References
- Validation of a reversed-phase HPLC method for 1,10-phenanthroline-5,6-dione and analysis of its impurities by HPLC-MS. | Shabir, GA. and Forrow, NJ. 2003. J Pharm Biomed Anal. 33: 219-30. PMID: 12972087
- ESI-MS studies of mixed-ligand Fe(II) complexes containing 1,10-phenanthroline and 1,10-phenanthroline-5,6-dione as ligands. | Kobetić, R., et al. 2008. J Mass Spectrom. 43: 753-64. PMID: 18205242
- 3a,11b-Dihy-droxy-3a,11b-dihydro-1H-imidazo[4,5-f][1,10]phenanthroline-2(3H)-thione. | Wang, H., et al. 2012. Acta Crystallogr Sect E Struct Rep Online. 68: o208. PMID: 22259489
- Water detection by 'turn on' fluorescence of the quinone-containing complexes [Ru(phen)2(1,10-phenanthroline-5,6-dione)2+] and [Ru(phenanthroline-5,6-dione)3]2+. | Poteet, SA. and MacDonnell, FM. 2013. Dalton Trans. 42: 13305-7. PMID: 23925310
- 1,10-Phenanthroline-5,6-dione ethanol monosolvate. | Dai, JW., et al. 2014. Acta Crystallogr Sect E Struct Rep Online. 70: o573. PMID: 24860377
- 1,10-Phenanthroline-5,6-Dione-Based Compounds Are Effective in Disturbing Crucial Physiological Events of Phialophora verrucosa. | Granato, MQ., et al. 2017. Front Microbiol. 8: 76. PMID: 28194139
- Reagent-less amperometric glucose biosensor based on a graphite rod electrode layer-by-layer modified with 1,10-phenanthroline-5,6-dione and glucose oxidase. | Kausaite-Minkstimiene, A., et al. 2017. Talanta. 171: 204-212. PMID: 28551130
- The semiquinone radical anion of 1,10-phenanthroline-5,6-dione: synthesis and rare earth coordination chemistry. | Hickson, JR., et al. 2018. Chem Commun (Camb). 54: 11284-11287. PMID: 30239538
- Mechanistic studies of in vitro anti-proliferative and anti-inflammatory activities of the Zn(ii)-NSAID complexes of 1,10-phenanthroline-5,6-dione in MDA-MB-231 cells. | Deb, J., et al. 2020. Dalton Trans. 49: 11375-11384. PMID: 32766641
- Antibacterial activity and carbapenem re-sensitizing ability of 1,10-phenanthroline-5,6-dione and its metal complexes against KPC-producing Klebsiella pneumoniae clinical strains. | Vianez Peregrino, I., et al. 2021. Lett Appl Microbiol. 73: 139-148. PMID: 33843058
- Silver(I) and Copper(II) Complexes of 1,10-Phenanthroline-5,6-Dione Against Phialophora verrucosa: A Focus on the Interaction With Human Macrophages and Galleria mellonella Larvae. | Granato, MQ., et al. 2021. Front Microbiol. 12: 641258. PMID: 34025603
- Anti-Leishmania braziliensis activity of 1,10-phenanthroline-5,6-dione and its Cu(II) and Ag(I) complexes. | Lima, AKC., et al. 2021. Parasitol Res. 120: 3273-3285. PMID: 34363115
- Oxidative damage by 1,10-phenanthroline-5,6-dione and its silver and copper complexes lead to apoptotic-like death in Trichomonas vaginalis. | Vargas Rigo, G., et al. 2023. Res Microbiol. 174: 104015. PMID: 36566772
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,10-Phenanthroline-5,6-dione, 1 g | sc-222781 | 1 g | $168.00 |