ZKSCAN3 Activators refers to a class of chemical compounds that modulate the activity of the ZKSCAN3 protein. ZKSCAN3, also known as zinc finger with KRAB and SCAN domains 3, is a transcriptional repressor that plays a crucial role in regulating gene expression. The protein is characterized by its zinc finger motifs and SCAN domains, which are involved in DNA binding and protein-protein interactions, respectively. ZKSCAN3 is primarily localized in the nucleus of cells, where it exerts its regulatory influence on target genes by interacting with specific DNA sequences.
Chemical compounds classified as ZKSCAN3 Activators are designed to enhance the activity of the ZKSCAN3 protein, presumably by promoting its binding to DNA or facilitating its interactions with other cellular components. The exact mechanism of action of these activators is likely intricate and involves molecular interactions that influence the conformation and function of ZKSCAN3. Researchers exploring this class of compounds aim to unravel the intricate details of how ZKSCAN3 Activators modulate gene expression, shedding light on the broader regulatory networks in which ZKSCAN3 participates. By understanding the molecular mechanisms underlying the activation of ZKSCAN3, scientists may gain valuable insights into the intricate dynamics of gene regulation, potentially opening avenues for further research in the field of cellular and molecular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An chemical that can enhance autophagy by inhibiting mTOR, a suppressor of autophagy. This impact on the autophagy pathway can indirectly enhance the functional activity of ZKSCAN3. | ||||||
D-(+)-Trehalose Anhydrous | 99-20-7 | sc-294151 sc-294151A sc-294151B | 1 g 25 g 100 g | $30.00 $167.00 $260.00 | 2 | |
A disaccharide sugar that can induce autophagy, thereby potentially enhancing the activity of ZKSCAN3. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium ions can stimulate autophagy by inhibiting inositol monophosphatase, which may lead to the enhanced activity of ZKSCAN3. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenolic compound that can stimulate AMPK, leading to inhibited mTOR activity, enhanced autophagy, and potentially enhanced ZKSCAN3 activity. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
An chemical that can inhibit mTOR signaling, enhancing autophagy and potentially enhancing the activity of ZKSCAN3. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
An HDAC inhibitor that can enhance autophagy, potentially leading to the enhanced activity of ZKSCAN3. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
A calcium channel blocker that can stimulate autophagy by reducing mTOR signaling, potentially enhancing the activity of ZKSCAN3. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
An estrogen receptor antagonist that can stimulate autophagy, potentially enhancing the activity of ZKSCAN3. | ||||||