WSB2 Activators
WD Repeat and SOCS Box-Containing Protein 2 (WSB2) is a protein encoded by the WSB2 gene in humans. It's part of the SOCS box protein family, which is characterized by the presence of a SOCS box domain.The SOCS box domain enables proteins like WSB2 to act as E3 ubiquitin ligases, which are key components of the ubiquitin-proteasome system. This system is involved in the degradation of proteins within the cell, playing a critical role in protein quality control and regulation of numerous cellular processes, such as signal transduction, cell cycle progression, and immune response.
WSB2 is also characterized by multiple WD repeats, which are motifs often involved in protein-protein interactions. These interactions can facilitate the assembly of multiprotein complexes, which are crucial for several cellular functions. Dysfunction or mutations in proteins like WSB2 lead to aberrant protein degradation, which has been linked to a variety of diseases, including neurodegenerative disorders and cancer. In summary, WSB2 is a protein with roles in protein degradation and regulation of various cellular processes. Further research is needed to fully understand its specific functions, regulation, and implications in health and disease.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
Lactacystin, another proteasome inhibitor, might indirectly affect WSB2 by altering protein degradation pathways. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
As a specific proteasome inhibitor, Bortezomib can indirectly influence WSB2 activity through its effects on the ubiquitin-proteasome pathway. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Thalidomide and its derivatives, known for modulating protein degradation, might indirectly affect WSB2 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, with its broad biological activities, might influence WSB2 indirectly through pathways related to protein ubiquitination and inflammation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, known for its effects on various signaling pathways, could indirectly affect WSB2 through mechanisms involving protein degradation and cell signaling. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a polyphenol in green tea, known for modulating protein degradation pathways, could indirectly influence WSB2 activity. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
Withaferin A, known to modulate proteasomal activity, could indirectly affect WSB2 by influencing the ubiquitin-proteasome system. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, a compound in cruciferous vegetables, may influence WSB2 indirectly through its effects on cellular detoxification and proteasome function. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Disulfiram, primarily used in alcohol dependence treatment, can indirectly affect WSB2 due to its ability to modulate proteasome activity. | ||||||
D-(+)-Trehalose Anhydrous | 99-20-7 | sc-294151 sc-294151A sc-294151B | 1 g 25 g 100 g | $30.00 $167.00 $260.00 | 2 | |
Trehalose, known for inducing autophagy, might indirectly influence WSB2 activity through pathways related to protein degradation. | ||||||