The nomenclature FLJ20433 Activators implies a theoretical group of chemical compounds devised to enhance the activity of the protein encoded by the FLJ20433 gene. The FLJ acronym typically denotes full-length long Japan, a naming convention arising from a project aimed at discovering full-length long cDNA sequences in the Japanese population. Activators is purely speculative and does not correspond to any known chemical class. Should such a protein exist and be identified, activators would be molecules that interact with this protein to upregulate its function. These activators could potentially work by a variety of mechanisms, such as binding to the protein to stabilize its active form, increasing its expression through transcriptional regulation, or enhancing its interaction with other cellular components. The specific chemical properties of FLJ20433 Activators would depend significantly on the tertiary and quaternary structure of the FLJ20433 protein, as well as its role within the cellular machinery.
In the scenario of FLJ20433 Activators' development, the first step would be to ascertain the biological function of the FLJ20433 protein. This would likely entail a combination of genomic, proteomic, and bioinformatic techniques to map out the protein's structure, its domains of activity, and its cellular localization. Understanding the protein's role within the cell would be pivotal, and this could involve delving into its involvement in cellular processes, its interaction networks, and its regulation both at the genetic and post-translational levels. Once a comprehensive understanding of FLJ20433 is obtained, attention would turn to the chemical design of activators. These activators would be synthesized based on the structure of the protein and predicted interaction sites using computational chemistry and molecular modeling. The design process would also draw on knowledge from related proteins or homologous systems, where available. Subsequent experimental phases would involve in vitro and in vivo assays to test the compounds' efficacy in activating the FLJ20433 protein. These assays would measure not only the binding affinity and specificity of the activators but also their capacity to modulate the protein's activity in a controlled manner. Through this iterative process of hypothesis, design, synthesis, and testing, a class of FLJ20433 Activators could potentially be produced, offering insight into the biological function of the protein and serving as molecular probes for further scientific inquiry.
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| Nome del prodotto | CAS # | Codice del prodotto | Quantità | Prezzo | CITAZIONI | Valutazione |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Provoca danni al DNA inibendo la ribonucleotide reduttasi, inducendo potenzialmente gli enzimi di riparazione del DNA, tra cui EXD3. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Forma addotti del DNA che provocano danni al DNA, con conseguente upregolazione delle proteine di riparazione del DNA come EXD3. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Induce rotture del filamento di DNA inibendo la topoisomerasi II, probabilmente aumentando l'espressione degli enzimi di riparazione del DNA. | ||||||
Methyl methanesulfonate | 66-27-3 | sc-250376 sc-250376A | 5 g 25 g | $55.00 $130.00 | 2 | |
Agente alchilante che causa danni al DNA, potenzialmente in grado di innescare l'espressione di vie di riparazione del DNA, tra cui EXD3. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Un'antraciclina che si intercala nel DNA, causando danni ed eventualmente inducendo meccanismi di riparazione del DNA. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Incrocia il DNA, determinando un aumento dell'attività di riparazione del DNA che potrebbe includere l'espressione di EXD3. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inibisce la topoisomerasi I, causando rotture del DNA e potenzialmente aumentando la regolazione degli enzimi di riparazione del DNA come EXD3. | ||||||
Bleomycin | 11056-06-7 | sc-507293 | 5 mg | $270.00 | 5 | |
Induce la scissione del DNA, aumentando potenzialmente l'espressione di geni coinvolti nella riparazione del DNA, come EXD3. | ||||||
Benzo[a]pyrene | 50-32-8 | sc-257130 | 1 g | $439.00 | 4 | |
Idrocarburo policiclico aromatico che forma addotti al DNA, inducendo potenzialmente l'espressione dei geni di riparazione del DNA. | ||||||
Acrylamide Solution, 40% | 79-06-1 | sc-3721 | 1 L | $98.00 | ||
Può formare addotti al DNA con conseguente danno genomico, potenzialmente in grado di regolare i meccanismi di riparazione del DNA, compresa l'espressione di EXD3. | ||||||