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Y-box binding protein YB-1 (also known as CCAAT-binding transcription factor, enhancer factor I subunit A and DNA-binding protein B) belongs to a family of multifunctional proteins which regulate both transcription and translation. Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins. The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing Arginine clusters and aromatic residues. YB-1 plays a role in cell proliferation as an activator of growth-associated gene expression. YB-1 is also a repressor of the cell death-associated gene FAS. YB-1 may play an important role in controlling cell survival by regulating the expression of cell growth-associated and death-associated genes.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps YB-1 (E-7) | sc-398146 | 200 µg/ml | $316.00 | |||
YB-1 (E-7): m-IgG Fc BP-HRP Kit | sc-538378 | 200 µg Ab; 10 µg BP | $354.00 | |||
YB-1 (E-7): m-IgGκ BP-HRP Kit | sc-535982 | 200 µg Ab; 40 µg BP | $354.00 | |||
YB-1 (E-7): m-IgG1 BP-HRP Kit | sc-545671 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps YB-1 (E-7) X | sc-398146 X | 200 µg/0.1 ml | $316.00 |