Date published: 2025-9-11

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Anticorps XLF (E-2): sc-393844

5.0(2)
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Fiches techniques
  • L'Anticorps XLF (E-2) est un monoclonal de souris IgG1 κ, cité dans 1 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-299 correspondant à la séquence totale de XLF d'origine human
  • recommandé pour la détection de XLF d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Réactifs TransCruz pour une application en ChIP (sc-393844 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps XLF (E-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps XLF (E-2)(voir les informations de commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

XLF (XRCC4-like factor), also known as non-homologous end-joining factor 1 (NHEJ1) or cernunnos, is a 295 amino acid protein belonging to the XLF family. There are two main repair pathways for DNA double-strand breaks: homologous recombination (HR) and non-homologous end-joining (NHEJ). In the latter pathway, the Ku-70/Ku-86 heterodimer binds the DNA ends together and the DNA-PK catalytic subunits are recruited. Then the DNA ends are processed by DNA processing enzymes, such as Artemis. The binding is finalized through DNA Ligase IV, which acts in a complex with XRCC4 and XLF to stabilize the repair. Thus, it is believed that XLF interacts with DNA Ligase IV and XRCC4 to constitute the enzymatic core of the NHEJ machinery. Two named isoforms of XLF exist as a result of alternative splicing events.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps XLF (E-2)

sc-393844
200 µg/ml
$316.00

XLF (E-2): m-IgG Fc BP-HRP Kit

sc-538321
200 µg Ab; 10 µg BP
$354.00

XLF (E-2): m-IgGκ BP-HRP Kit

sc-535905
200 µg Ab; 40 µg BP
$354.00

XLF (E-2): m-IgG1 BP-HRP Kit

sc-545639
200 µg Ab; 20 µg BP
$354.00

Anticorps XLF (E-2) X

sc-393844 X
200 µg/0.1 ml
$316.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-393844: XLF (E-2) mouse monoclonal antibody will work?

Posée par: TinTin
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Répondue par: Technical Support
Date de publication: 2017-03-06
  • y_2025, m_9, d_7, h_4CST
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Rated 5 de 5 de par Nice Western Blot data of XLF expression in nonNice Western Blot data of XLF expression in non-transfected and mouse XLF transfected 293T whole cell lysates. -SCBT QC
Date de publication: 2015-03-10
Rated 5 de 5 de par Nice Western Blot data of XLF expression in HeLaNice Western Blot data of XLF expression in HeLa, Jurkat and A-431 whole cell lysates. -SCBT QC
Date de publication: 2013-01-31
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Anticorps XLF (E-2) est évalué 5.0 de 5 de 2.
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