Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. VEZF1 (vascular endothelial zinc finger 1), also known as ZNF161 or DB1, is a nuclear localizing zinc-finger protein belonging to the Krüppel C2H2-type zinc-finger family. Expressed throughout the body with the highest level of expression found in the kidneys and skeletal muscle, VEZF1 is an endothelial transcription factor that regulates ET-1 (endothelin-1) promoter expression. Through its interaction with the CT/GC-rich region of the ET-1 promoter, VEZF1 helps to regulate proper assembly of the cardiovascular system during early development by activating the expression of various genes found in the vascular endothelium.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps VEZF1 (C-10) | sc-365561 | 200 µg/ml | $316.00 | |||
VEZF1 (C-10): m-IgG Fc BP-HRP Kit | sc-537815 | 200 µg Ab; 10 µg BP | $354.00 | |||
VEZF1 (C-10): m-IgGκ BP-HRP Kit | sc-535222 | 200 µg Ab; 40 µg BP | $354.00 | |||
VEZF1 (C-10): m-IgG1 BP-HRP Kit | sc-545373 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps VEZF1 (C-10) X | sc-365561 X | 200 µg/0.1 ml | $316.00 |