Anticorps UNC45A (D-6): sc-390211
- L'Anticorps UNC45A (D-6) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
- soulevée contre une cartographie peptidique au niveau de C-terminus de UNC45A de human d'origine
- recommandé pour la détection de UNC45A d'origine mouse, rat et human par WB, IP, IF et ELISA
- 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps UNC45A (D-6) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps UNC45A (D-6)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
UNC45A (unc-45 homolog A), also known as SMAP1 (Smooth muscle cell-associated protein 1) or GCUNC45, is a 944 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains three TPR repeats. Expressed in spinal cord, bone marrow, peripheral blood leukocytes, trachea, stomach and adrenal gland, UNCA45A functions as a chaperone for HSP 90, effectively facilitating the association of HSP 90 with PR (progesterone receptor). Additionally, UNC45A is thought to be necessary for proper folding of Myosin and is required for normal myotube formation during muscle cell development, thereby playing an important role in muscle formation. Overexpression of UNC45A is associated with rapid cell proliferation and motility, especially that observed in ovarian cancer, suggesting a role for UNC45A in tumorigenesis. Multiple isoforms of UNC45A exist due to alternative splicing events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UNC45A (D-6) | sc-390211 | 200 µg/ml | $316.00 | |||
UNC45A (D-6): m-IgGκ BP-HRP Kit | sc-535601 | 200 µg Ab; 40 µg BP | $354.00 | |||
UNC45A (D-6): m-IgG2b BP-HRP Kit | sc-549454 | 200 µg Ab; 10 µg BP | $354.00 | |||
UNC45A (D-6) peptide neutralisant | sc-390211 P | 100 µg/0.5 ml | $68.00 |