UBE1L Antibody (G-11): sc-390238
- UBE1L Antibody (G-11) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 163-370 mapping within an internal region of UBE1L of human origin
- recommended for detection of UBE1L of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for UBE1L Antibody (G-11) for WB applications. These reagents are now offered in bundles with UBE1L Antibody (G-11) (see ordering information below).
UBE1L Antibody (G-11) is a mouse monoclonal IgG2a antibody that detects UBE1L in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). UBE1L, also known as Ubiquitin-activating enzyme E1 homolog or UBA7, plays a crucial role in the ubiquitin-proteasome pathway, which is essential for regulating protein degradation and maintaining cellular homeostasis. This 1011 amino acid protein is particularly significant in tumor biology, as UBE1L is expressed in tumor cells and serves as a target for retinoids, which can induce apoptosis in acute promyelocytic leukemia by promoting the conjugation of ubiquitin-like modifier ISG15 to cellular proteins. UBE1L′s ability to activate ubiquitin through ATP-dependent adenylation highlights UBE1L′s importance in cellular signaling and the regulation of various biological processes, making anti-UBE1L antibody (G-11) a valuable tool for researchers studying cancer and protein degradation pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBE1L Antibody (G-11) | sc-390238 | 200 µg/ml | $322.00 | |||
UBE1L Antibody (G-11): m-IgG Fc BP-HRP Bundle | sc-540776 | 200 µg Ab; 10 µg BP | $361.00 | |||
UBE1L Antibody (G-11): m-IgG2a BP-HRP Bundle | sc-546955 | 200 µg Ab; 10 µg BP | $361.00 |