Anticorps UBC9 (67AT1273.95.90): sc-130281
- L'anticorps UBC9 67AT1273.95.90 est un monoclonal IgG1 de souris, cité dans 2 publications, fourni en 100 µg/ml
- recommandé pour la détection de UBC9 d'origine human par WB, IP et ELISA
- Voir UBC9 (C-12): sc-271057 pour d'autres anticorps conjugués UBC9, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire UBC9 (67AT1273.95.90). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
UBC9 is a component of the ubiquitin-mediated proteolytic pathway, which targets proteins for degradation by the 26S proteasome, mediates endocytosis and directs protein subcellular localization. Ub and Ub-like molecules are systematically transferred from E2 conjugating enzymes to the targeted substrate by way of an E3 ubiquitin ligase. UBC9 functions as an E2 ubiquitin conjugating enzyme that preferentially associates with the ubiquitin homolog designated SUMO-1 or sentrin, a component of the sentrinization complex. Characteristic of the E2 family members, UBC9 contains a conserved cysteine residue that is required for the thio ester formation between Ub-like proteins and the E2 member, and it shares a conserved UBC domain. Substrates for UBC9 include transcription factors E12 and E47 and mitotic regulators RanBP2 and RanGAP1, which indicates that UBC9 may regulate various cellular processes including cell cycle progression and differentiation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps UBC9 (67AT1273.95.90) | sc-130281 | 100 µg/ml | $316.00 |