ACCÈS RAPIDE AUX LIENS
TUSC5 (tumor suppressor candidate 5), also known as protein located at 17p13.3, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain. The gene encoding TUSC5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is linked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TUSC5 (C-5) | sc-514114 | 200 µg/ml | $316.00 | |||
TUSC5 (C-5): m-IgG Fc BP-HRP Kit | sc-538584 | 200 µg Ab; 10 µg BP | $354.00 | |||
TUSC5 (C-5): m-IgGκ BP-HRP Kit | sc-536225 | 200 µg Ab; 40 µg BP | $354.00 | |||
TUSC5 (C-5): m-IgG1 BP-HRP Kit | sc-545782 | 200 µg Ab; 20 µg BP | $354.00 |