Date published: 2025-9-7

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Anticorps TSEN54 (A-9): sc-398327

5.0(2)
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Fiches techniques
  • L'Anticorps TSEN54 (A-9) est un monoclonal de souris IgG2b (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 111-128 au niveau d'une région interne de TSEN54 d'origine human
  • recommandé pour la détection de TSEN54 d'origine mouse, rat et human par WB, IP, IF et ELISA; également réactif avec d'autres espèces, dont et equine, canine and bovine
  • 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps TSEN54 (A-9) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps TSEN54 (A-9)(voir les informations relatives à la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5′ and 3′ splice sites, thereby releasing introns and free tRNA molecules with 2′,3′ cyclic phosphates and 5′-OH termini. In addition to its role in pre-tRNA splicing, the heterotetrameric endonuclease complex participates in mRNA processing and, via its association with pre-mRNA processing factors, is thought to link pre-tRNA and pre-mRNA splicing events. TSEN54 (tRNA splicing endonuclease 54 homolog), also known as HsSEN54 (SEN54 homolog) or tRNA-intron endonuclease Sen54, is a 526 amino acid protein belonging to the SEN54 family. Localizing to nucleus, TSEN54 is a member of a complex which identifies and cleaves the splice sites in pre-tRNA, and may also be involved in mRNA processing. Defects in TSEN54 may result in pontocerebellar hypoplasia (PCH) type 4 and 2A, characterized by structural abnormalities to the cerebellum, inferior olive, and ventral pons. TSEN54 exists as two alternatively spliced isoforms.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps TSEN54 (A-9)

sc-398327
200 µg/ml
$316.00

TSEN54 (A-9): m-IgGκ BP-HRP Kit

sc-536031
200 µg Ab; 40 µg BP
$354.00

TSEN54 (A-9): m-IgG2b BP-HRP Kit

sc-549505
200 µg Ab; 10 µg BP
$354.00

TSEN54 (A-9) peptide neutralisant

sc-398327 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-398327 P appropriate for?

Posée par: cjMara
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Répondue par: Technical Support
Date de publication: 2017-03-01
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Rated 5 de 5 de par Beautiful immunofluorescence nucleolar andBeautiful immunofluorescence nucleolar and nuclear staining in methanol-fixed HeLa cells. -SCBT QC
Date de publication: 2015-01-07
Rated 5 de 5 de par Great Western Blot data of TSEN54 expressionGreat Western Blot data of TSEN54 expression in non-transfected 293T, human TSEN54 transfected 293T and Y79 whole cell lysates. -SCBT QC
Date de publication: 2014-05-03
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Anticorps TSEN54 (A-9) est évalué 5.0 de 5 de 2.
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