Anticorps Trx (1H6H6): sc-81155
- L'Anticorps Trx (1H6H6) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre la Trx recombinante d'origine human
- recommandé pour la détection de Trx d'origine human par WB et IP
- Voir Trx (A-5): sc-166393 pour d'autres anticorps conjugués Trx, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Trx Antibody (1H6H6) for WB applications. Ces réactifs sont désormais proposés en lots avec Trx Antibody (1H6H6)(voir les informations de commande ci-dessous).
Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Trx (1H6H6) | sc-81155 | 200 µg/ml | $316.00 | |||
Trx (1H6H6): m-IgG Fc BP-HRP Kit | sc-539592 | 200 µg Ab; 10 µg BP | $354.00 | |||
Trx (1H6H6): m-IgG1 BP-HRP Kit | sc-541582 | 200 µg Ab; 20 µg BP | $354.00 |