TrkA family transport protein Antibody (A-9): sc-398728

TrkA family transport protein Antibody (A-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects TrkA family transport protein of Streptococcus equi subsp. equi 4047 origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TrkA family transport protein Antibody (A-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TrkA family transport protein (A-9) antibody recognizes a membrane-bound protein that plays a crucial role in transporting essential nutrients across the bacterial cell membrane, vital for the survival and virulence of Streptococcus equi subspecies equi. Anti-TrkA family transport protein antibody (A-9) targets a protein located in the bacterial membrane, where specific substrates necessary for metabolic processes and growth are transported. Understanding TrkA family transport protein′s function and location provides insights into potential therapeutic targets for treating infections caused by this pathogen. Streptococcus equi subspecies equi causes strangles, a highly contagious disease in horses characterized by severe respiratory symptoms and lymphadenitis, making transport protein research critical for developing effective interventions.

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TrkA family transport protein Antibody (A-9) References:

1. Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection.  |  Guss, B., et al. 2009. PLoS Pathog. 5: e1000584. PMID: 19763180
2. Molecular characterisation of 'strangles' outbreaks in the UK: the use of M-protein typing of Streptococcus equi ssp. equi.  |  Ivens, PA., et al. 2011. Equine Vet J. 43: 359-64. PMID: 21492215
3. Association of Streptococcus equi with equine monocytes.  |  Mérant, C., et al. 2011. Vet Immunol Immunopathol. 143: 83-6. PMID: 21752476
4. Streptococcus equi: a pathogen restricted to one host.  |  Waller, AS., et al. 2011. J Med Microbiol. 60: 1231-1240. PMID: 21757503
5. Streptococcus equi subspecies equi infection (strangles) in horses.  |  Boyle, A. 2011. Compend Contin Educ Vet. 33: E1-7; quiz E8. PMID: 21870348
6. Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component.  |  Flock, M., et al. 2012. Infect Immun. 80: 2914-9. PMID: 22615244
7. Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model.  |  Rodrigues, MA., et al. 2012. Eur J Pharm Biopharm. 82: 392-400. PMID: 22841882
8. Detection of Streptococcus equi subspecies equi using a triplex qPCR assay.  |  Webb, K., et al. 2013. Vet J. 195: 300-4. PMID: 22884566
9. Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1).  |  Drilon, A., et al. 2017. Cancer Discov. 7: 400-409. PMID: 28183697
10. HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury.  |  Krzystek, TJ., et al. 2023. Autophagy. 19: 1199-1220. PMID: 36048753
11. Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.  |  Guo, Y., et al. 2024. Signal Transduct Target Ther. 9: 32. PMID: 38351062
12. NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.  |  Schlösser, A., et al. 1993. Mol Microbiol. 9: 533-43. PMID: 8412700

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-TrkA family transport protein Antibody (A-9) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

TrkA family transport protein Antibody (A-9) Specifications

Alternate Product Name: TrkA family transport protein

Product Clone Name: A-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-224

Epitope Target: TrkA family transport protein

Epitope Species: Streptococcus equi subsp. equi 4047

Product Reactivity/Detection: TrkA family transport protein

Species Reactivity/Detection: Streptococcus equi subsp. equi 4047

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for TrkA family transport protein Antibody (A-9): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin