Anticorps Trk C (WW6): sc-80403
- L'Anticorps Trk C (WW6) est un monoclonal de souris IgG2b κ, cité dans 3 publications, fourni en 100 µg/ml
- soulevée contre un domaine extracellulaire de Trk C d'origine human.
- recommandé pour la détection de Trk C d'origine human par WB, IF et IHC(P); non cross-reactif avec Trk B
- Voir Trk (B-3): sc-7268 pour d'autres anticorps conjugués Trk C, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Trk C (WW6). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The Trk proto-oncogene encodes a tyrosine protein kinase, Trk A, also designated Trk gp140, that serves as a receptor for certain neurotrophic factors including nerve growth factor (NGF) and neurotrophin-3 (NT-3). Trk B is a tyrosine kinase gene highly related to Trk A. Trk B expression is confined to tissues within the central and peripheral nervous systems. The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on Tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3. Thus it appears that Trk B gp145 may represent a neurotrophic receptor for BDNF and NT-3. The third member of the Trk family of tyrosine kinases, Trk C, is mainly expressed in nervous tissue, and is a functional receptor for NT-3. Four forms of Trk C are produced by alternative splicing. Isoform A is full length Trk C, isoform B differs from A between amino acids 529 to 612 and is missing amino acids 613 to 839. Trk C, isoform C is missing amino acids 712 to 725 and isoform D is missing amino acids 402 to 410.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Trk C (WW6) | sc-80403 | 100 µg/ml | $316.00 |