TRAF5 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. TRAF5 is one of the components of a complex associated with the CD40 cytoplasmic domain, which mediates TNF induced NF-kappa B activation and protection from cell death. TRAF5 influences signaling events by other receptors including CD27, CD30, and lymphotoxin-beta receptor. TRAF5 plays a role in osteoclastogenesis. Two alternatively spliced transcript variants encoding the same protein have been reported. The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine-rich extracellular domains.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TRAF5 (E-5) | sc-74503 | 200 µg/ml | $316.00 | |||
TRAF5 (E-5): m-IgG Fc BP-HRP Kit | sc-539534 | 200 µg Ab; 10 µg BP | $354.00 | |||
TRAF5 (E-5): m-IgG1 BP-HRP Kit | sc-541548 | 200 µg Ab; 20 µg BP | $354.00 |