TMED2 (transmembrane emp24 domain trafficking protein 2), also known as P24A or RNP24, is a 201 amino acid protein that is a member of the EMP24/GP25L family. Like most members of this family, TMED2 is a single-pass type I membrane protein containing one GOLD domain. The GOLD (golgi dynamics) domain is a region of about 90 to 150 amino acids that mediates protein-protein interactions. The GOLD domain interacts with lipid, sterol or fatty acid-domains as well as with RUN domains, which interact with cytoskeletal filaments of membrane proteins. TMED2 is thought to inhibit GTPase-activating activity of ARFGAP1 and may have a role in the budding of coatomer-coated and other species of coated vesicles. As part of a complex composed of SURF-4 and TMP21, TMED2 binds to cargo molecules to collect them into budding vesicles.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TMED2 (A-8) | sc-376033 | 200 µg/ml | $316.00 | |||
TMED2 (A-8): m-IgG Fc BP-HRP Kit | sc-540500 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMED2 (A-8): m-IgG1 BP-HRP Kit | sc-542162 | 200 µg Ab; 20 µg BP | $354.00 |