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TH-POK (T-helper-inducing POZ/Krüppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Krüppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and fibronectin.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TH-POK (C-8) | sc-398509 | 200 µg/ml | $316.00 | |||
TH-POK (C-8): m-IgG Fc BP-HRP Kit | sc-540937 | 200 µg Ab; 10 µg BP | $354.00 | |||
TH-POK (C-8): m-IgG2a BP-HRP Kit | sc-546982 | 200 µg Ab; 10 µg BP | $354.00 | |||
TH-POK (C-8) peptide neutralisant | sc-398509 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps TH-POK (C-8) X | sc-398509 X | 200 µg/0.1 ml | $316.00 |