T cell leukemia/lymphoma protein 1B (TCL-1B), also designated TML1, TCL/MTCP1-like 1, syncytiotrophoblast-specific protein and SYN-1, is involved in T cell prolymphocytic leukemia (T-PLL). TCL-1B is located within the region on human chromosome 14q32.1 which, in T cell leukemias and lymphomasis, is frequently involved in chromosomal translocations and inversions with one of the T cell receptor loci. TCL-1B is activated by chromosomal rearrangements involving the TCL1 locus. In mouse, TCL-1B is represented by five homologues, TCL-1B1-TCL-1B5. The crystal structure of TCL-1B suggests that it may play a role in the transport of small molecules such as retinoids, nucleotides and fatty acids. TCL-1B is found in both the nucleus and the cytoplasm of normal bone marrow and peripheral lymphocytes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TCL-1B (NDOG1) | sc-57478 | 200 µg/ml | $316.00 | |||
TCL-1B (NDOG1): m-IgGκ BP-HRP Kit | sc-534330 | 200 µg Ab; 40 µg BP | $354.00 | |||
Anticorps TCL-1B (NDOG1) FITC | sc-57478 FITC | 200 µg/ml | $330.00 | |||
Anticorps TCL-1B (NDOG1) PE | sc-57478 PE | 200 µg/ml | $343.00 |