Anticorps TBL1 (A-3): sc-137082
- L'Anticorps TBL1 (A-3) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 211-577 de TBL1X d'origine human
- recommandé pour la détection de TBL1X of mouse, rat and human origin and TBL1Y of human origin par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-137082 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour TBL1 Antibody (A-3) for WB applications. Ces réactifs sont désormais proposés en lots avec TBL1 Antibody (A-3)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
TBL1, for transducin β-like 1, is a ubiquitously expressed protein that contains six distinct β-transducin repeats, known also as WD40 repeats, within the C-terminal domain. Transducin β-like 1 Y-linked protein (TBL1Y), also designated F-box-like/WD-repeat protein, and transducin β-like 1 X protein (TBL1X), also known as SMAP55, are nuclear F-box-like proteins. They are important in the ubiquitin/19S proteasome complex recruitment to nuclear receptor-regulated transcription units. TBL1X is a part of the N-CoR repressor complex together with N-CoR1, N-CoR2, HDAC3, TBL1R, CORO2A and GPS2. It is also a component of the E3 ubiquitin ligase complex. TBL1X, which can interact with Histones H2B, H3a and H4, is similar to TBL1Y but is localized on chromosome Xp22.3. Defects in TBL1X may cause an X-linked human disorder called ocular albinism with late-onset sensorineural deafness (OASD). TBL1Y is an X-degenerate gene that is homologous to TBL1X. TBL1Y, a single-copy gene, localizes to human chromosome Yp11.2 in the male-specific region of chromosome Y (MSY). This region of the Y chromosome does not engage in X-Y crossover events. TBL1Y is primarily expressed in fetal brain and prostate. TBL1X and TBL1Y are crucial in nuclear receptor mediated transcription activation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps TBL1 (A-3) | sc-137082 | 200 µg/ml | $316.00 | |||
TBL1 (A-3): m-IgG Fc BP-HRP Kit | sc-539930 | 200 µg Ab; 10 µg BP | $354.00 | |||
TBL1 (A-3): m-IgG1 BP-HRP Kit | sc-541793 | 200 µg Ab; 20 µg BP | $354.00 | |||
Anticorps TBL1 (A-3) X | sc-137082 X | 200 µg/0.1 ml | $316.00 |