ACCÈS RAPIDE AUX LIENS
VOIR ÉGALEMENT...
T3JAM (TRAF3 interacting protein 3), also known as TRAF3-interacting JNK-activating modulator or TRAF3IP3, is a 551 amino acid single-pass type IV membrane protein that acts as an adaptor molecule and stimulates cell growth by modulating the c-Jun N-terminal kinase (JNK) pathway in conjunction with TRAF3. Expressed in thymus, bone marrow and spleen, T3JAM binds the isoleucine zipper of TRAF3 with its coiled-coil domain. T3JAM has been found to associate specifically with TRAF3 but not with other TRAF family members. As a result of alternative splicing events, three T3JAM isoforms exist. The gene encoding T3JAM maps to human chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps T3JAM (H-2) | sc-398895 | 200 µg/ml | $316.00 | |||
T3JAM (H-2): m-IgG Fc BP-HRP Kit | sc-538541 | 200 µg Ab; 10 µg BP | $354.00 | |||
T3JAM (H-2): m-IgGκ BP-HRP Kit | sc-536174 | 200 µg Ab; 40 µg BP | $354.00 |