T-FABP Antibody (D-8): sc-390686
- T-FABP Antibody (D-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 20-39 of T-FABP of mouse origin
- recommended for detection of T-FABP of mouse and rat origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for T-FABP Antibody (D-8) for WB applications. These reagents are now offered in bundles with T-FABP Antibody (D-8) (see ordering information below).
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T-FABP Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects T-FABP in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). T-FABP, also known as PERF, FABP9, or PERF15, is a member of the fatty acid-binding protein family and is specifically expressed in testicular germ cells during spermatogenesis, playing a crucial role in germ cell development. T-FABP (D-8) antibody enables detection of T-FABP in the testis, suggesting a specialized function in the transport and metabolism of fatty acids, which are vital for the energy needs and membrane synthesis of developing sperm cells. By facilitating the uptake and intracellular transport of fatty acids, T-FABP contributes to the overall lipid homeostasis necessary for proper spermatogenesis, highlighting its significance in male fertility. Anti-T-FABP antibody (D-8) provides a reliable tool for researchers investigating the role of fatty acid-binding proteins in reproductive biology and related fields.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
T-FABP Antibody (D-8) References:
- FABP3 protein promotes α-synuclein oligomerization associated with 1-methyl-1,2,3,6-tetrahydropiridine-induced neurotoxicity. | Shioda, N., et al. 2014. J Biol Chem. 289: 18957-65. PMID: 24855640
- Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization. | Cheng, A., et al. 2019. Brain Res. 1707: 190-197. PMID: 30496735
- Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice. | Matsuo, K., et al. 2021. Brain Res. 1760: 147383. PMID: 33636166
- FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway. | Zhuang, L., et al. 2021. Front Cardiovasc Med. 8: 722908. PMID: 34458345
- FABP3 overexpression promotes vascular fibrosis in Takayasu's arteritis by enhancing fatty acid oxidation in aorta adventitial fibroblasts. | Wu, S., et al. 2022. Rheumatology (Oxford). 61: 3071-3081. PMID: 34718429
- Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma. | Zhang, X., et al. 2022. Cancer Commun (Lond). 42: 287-313. PMID: 35184419
- Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression. | Liu, Z., et al. 2022. Oncoimmunology. 11: 2085432. PMID: 35712121
- Fatty acid-binding proteins 3 and 5 are involved in the initiation of mitochondrial damage in ischemic neurons. | Guo, Q., et al. 2023. Redox Biol. 59: 102547. PMID: 36481733
- Novel FABP3 ligand, HY-11-9, ameliorates neuropathological deficits in MPTP-induced Parkinsonism in mice. | Wang, H., et al. 2023. J Pharmacol Sci. 152: 30-38. PMID: 37059489
- FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury. | Zhong, FF., et al. 2024. Neurotox Res. 42: 35. PMID: 39008165
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
T-FABP Antibody (D-8) | sc-390686 | 200 µg/ml | $322.00 | |||
T-FABP Antibody (D-8): m-IgG Fc BP-HRP Bundle | sc-540834 | 200 µg Ab; 10 µg BP | $361.00 | |||
T-FABP Antibody (D-8): m-IgG1 BP-HRP Bundle | sc-542402 | 200 µg Ab; 20 µg BP | $361.00 | |||
T-FABP (D-8) Neutralizing Peptide | sc-390686 P | 100 µg/0.5 ml | $69.00 |