Date published: 2025-9-7

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Anticorps SWAP-70 (Q-28): sc-81991

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Fiches techniques
  • L'Anticorps SWAP-70 (Q-28) est un monoclonal de souris IgG2a κ, cité dans 2 publications, fourni en 50 µg/0.5 ml
  • dirigé contre la SWAP-70 recombinante d'origine human
  • recommandé pour la détection de SWAP-70 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SWAP-70 (Q-28). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

SWAP-70 is a protein that is part of a protein complex that catalyzes cell-free DNA recombination between immunoglobulin (Ig) heavy chain gene switch region substrates. In resting B lymphocytes, SWAP-70 is localized mainly in the cytoplasm, however, in activated B cells, SWAP-70 is recruited to the plasma membrane and then translocates to the nucleus. In the nucleus, SWAP-70 recognizes specific switch regions, acting as a switch recombinase and causing a DNA break. The cellular and intracellular localization before and after B-cell activation also suggests a role for SWAP-70 in signaling in B cell activation. In addition, SWAP-70 contains three nuclear localization signals, has a weak affinity for DNA, binds ATP, and forms specific, high affinity complexes with B23, C23, and poly (ADP-ribose) polymerase.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps SWAP-70 (Q-28)

sc-81991
50 µg/0.5 ml
$333.00

Can sc-81991: SWAP-70 (Q-28) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: jenniferc
Thank you for your question. Yes, sc-81991: SWAP-70 (Q-28) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2018-11-26
  • y_2025, m_8, d_28, h_5CST
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Rated 5 de 5 de par WB publishable data with human HeLa cellsWB publishable data with human HeLa cells - SCBT Publication Review
Date de publication: 2015-04-08
Rated 5 de 5 de par Beautiful immunoperoxidase membrane and cytoplasmicBeautiful immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human spleen tissue. -SCBT QC
Date de publication: 2014-09-11
  • y_2025, m_8, d_28, h_5
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Anticorps SWAP-70 (Q-28) est évalué 5.0 de 5 de 2.
  • y_2025, m_8, d_28, h_5
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