Anticorps SULT2B1 (C-1): sc-166346
- L'Anticorps SULT2B1 (C-1) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 283-312 près de C-terminus de SULT2B1 d'origine human
- recommandé pour la détection de SULT2B1 isoforms 1 and 2 d'origine mouse, rat et human par WB, IP, IF et ELISA
- 1 BP-HRP">m-IgG1 BP-HRP est le réactif de détection secondaire préféré pour l'anticorps SULT2B1 (C-1) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps SULT2B1 (C-1)(voir les informations relatives à la commande ci-dessous).
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones. Members of the three groups comprising this superfamily show selectivity to certain substrate compounds. SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SULT2B1 (C-1) | sc-166346 | 200 µg/ml | $316.00 | |||
SULT2B1 (C-1): m-IgG1 BP-HRP Kit | sc-542660 | 200 µg Ab; 20 µg BP | $354.00 | |||
SULT2B1 (C-1) peptide neutralisant | sc-166346 P | 100 µg/0.5 ml | $68.00 |