ACCÈS RAPIDE AUX LIENS
STAMBP (STAM binding protein), also known as AMSH, is a 424 amino acid protein belonging to the peptidase M67C family. Ubiquitously expressed, STAMBP functions as a zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. STAMBP is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. STAMBP may play a role in signal transduction for cell growth and Myc induction mediated by IL-2 and GM-CSF. It is suggested that STAMBP potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of Smad6 and Smad7. STAMBP consists of the JAMM motif, which is essential for the protease activity, and is inhibited by N-ethylmaleimide.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps STAMBP (F-1) | sc-393408 | 200 µg/ml | $316.00 | |||
STAMBP (F-1): m-IgG Fc BP-HRP Kit | sc-538208 | 200 µg Ab; 10 µg BP | $354.00 | |||
STAMBP (F-1): m-IgGκ BP-HRP Kit | sc-535776 | 200 µg Ab; 40 µg BP | $354.00 | |||
STAMBP (F-1): m-IgG1 BP-HRP Kit | sc-545578 | 200 µg Ab; 20 µg BP | $354.00 | |||
STAMBP (F-1) peptide neutralisant | sc-393408 P | 100 µg/0.5 ml | $68.00 |