Anticorps SSX (C-9): sc-137073
- L'Anticorps SSX (C-9) est un monoclonal de souris IgG2b κ, cité dans 1 publications, fourni en 200 µg/ml
- raised against amino acids 1-188 representing full length SSX11 of human origin
- recommandé pour la détection de SSX1-SSX9 d'origine human par WB, IP, IF et ELISA
- Réactifs TransCruz pour une application en ChIP (sc-137073 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, 2b BP-HRP">m-IgG2b BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SSX (C-9) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SSX (C-9)(voir les informations de commande ci-dessous).
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators. SYT-SSX chimeras are detected in most synovial sarcomas. Synovial sarcomas are responsible for up to 10% of soft issue sarcomas and are histologically characterized as either biphasic or mono-phasic. Genetic analysis indicates that biphasic synovial sarcomas contain SYT-SSX1 fusions, whereas SYT-SSX2 fusions are found in monophasic synovial sarcomas, providing additional distinguishing characterization of these subtypes.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SSX (C-9) | sc-137073 | 200 µg/ml | $316.00 | |||
SSX (C-9): m-IgG Fc BP-HRP Kit | sc-537397 | 200 µg Ab; 10 µg BP | $354.00 | |||
SSX (C-9): m-IgGκ BP-HRP Kit | sc-534651 | 200 µg Ab; 40 µg BP | $354.00 | |||
SSX (C-9): m-IgG2b BP-HRP Kit | sc-549866 | 200 µg Ab; 10 µg BP | $354.00 | |||
Anticorps SSX (C-9) X | sc-137073 X | 200 µg/0.1 ml | $316.00 |