SPT3 Antibody (71-S) is an IgM mouse monoclonal SPT3 antibody that detects SPT3 of human origin by WB, IP and ELISA. SPT3 Antibody (71-S) is available as the non-conjugated anti-SPT3 antibody form. The Saccharomyces cerevisiae SAGA complex is a multifunctional coactivator that regulates transcription by RNA polymerase II. In yeast, SPT3 is a component of the multiprotein SPT-ADA-GCN5 acetyltransferase (SAGA) complex that integrates proteins with transcription coactivator/adaptor functions, histone acetyltransferase activity, and core promoter-selective functions involving interactions with the TATA-binding protein. The human STAGA complex contains homologs of most yeast SAGA components. STAGA has acetyl coenzyme A-dependent transcriptional coactivator functions from a chromatin-assembled template in vitro and associates in HeLa cells with spliceosome-associated proteins. Amino acid sequence comparisons between human SPT3 and its counterparts in yeast reveal three highly conserved domains, with the most conserved 92-amino acid N-terminal domain being 25% identical with human TAFII18.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SPT3 (71-S) | sc-101157 | 200 µl ascites | $333.00 |