Date published: 2025-9-9

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Anticorps SPF30 (SQ-16): sc-100338

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Fiches techniques
  • L'Anticorps SPF30 (SQ-16) est un monoclonal de souris mouse IgG1 κ (chaîne légère kappa) fourni en 50 µg/0.5 ml
  • dirigé contre la SPF30 recombinante d'origine human
  • recommandé pour la détection de SPF30 d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SPF30 (SQ-16). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (Survival Motor Neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest at prespliceosomes (A complex). This supports a function for SPF30 in mediating the incorporation/recruitment of U4/U5/U6 tri-snRNP to the prespliceosome. In addition, the overexpression of SPF30 can lead to apoptosis.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps SPF30 (SQ-16)

    sc-100338
    50 µg/0.5 ml
    $316.00

    Can sc-100338: SPF30 (SQ-16) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: DefinitelyNotMatt
    Thank you for your question. Yes, sc-100338: SPF30 (SQ-16) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-03-24
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    Rated 4 de 5 de par Great immunoperoxidase nuclear staining inGreat immunoperoxidase nuclear staining in formalin-fixed, paraffin-embedded human testis tissue. -SCBT QC
    Date de publication: 2015-03-12
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    Anticorps SPF30 (SQ-16) est évalué 4.0 de 5 de 2.
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