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Spectrin is an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin β II, which is involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus a candidate for the calcium-dependent movement of the cytoskeleton at the membrane.The human SPTBN1 gene encodes the nonerythroid form of β-spectrin.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps spectrin β II (H-5) | sc-374125 | 200 µg/ml | $316.00 | |||
spectrin β II (H-5): m-IgGκ BP-HRP Kit | sc-535391 | 200 µg Ab; 40 µg BP | $354.00 | |||
spectrin β II (H-5): m-IgG3 BP-HRP Kit | sc-550308 | 200 µg Ab; 40 µg BP | $354.00 | |||
spectrin β II (H-5) peptide neutralisant | sc-374125 P | 100 µg/0.5 ml | $68.00 |