Sodium Salicylate (CAS 54-21-7)
Sodium salicylate is a metabolite of acetylsalicylic acid (sc-217570), and functions by inhibiting NF κ B and reduces oxidative stress. The agent has the ability to protect against neurotoxicity induced by glutamate in rat studies. Along with aspirin (sc-202471), sodium salicylate is an anti-inflammatory compound that binds to and inhibits IKK β. Sodium salicylate has been shown to reduce ATP binding in vitro and in vivo. Sodium Salicylate is an inhibitor of c-Jun and Cox-2 and an activator of p38.
Références
1. Kopp, E. and Ghosh, S. 1994. Science. 265: 956-959. PMID: 8052854
2. Grilli, M., et al. 1996. Science. 274: 1383-1385. PMID: 8910280
3. Yin, M.J., et al. 1998. Nature. 396: 77-80. PMID: 9817203
4. Fan, J.R., et al. 2010. Eur. J. Pharmacol. 638: 13-20. PMID: 20406630
5. He, B., et al. 2010. Hepatobiliary Pancreat Dis Int. 9: 49-53. PMID: 20133229
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Sodium Salicylate (CAS 54-21-7) Références bibliographiques
Consultez les publications faisant référence à l' utilisation de Sodium Salicylate (CAS 54-21-7). Cliquez sur le lien pour afficher lentrée PubMed .
PMID: # 25616959 2015. Translational research : the journal of laboratory and clinical medicine. 166: 1-11.
PMID: # 23175182 Ciceroni, C. et al. 2013. Cell Death Differ. 20: 396-407.
PMID: # 20133229 He, B. et al. 2010. HBPD INT. 9: 49-53.
PMID: # 9096313 Schwenger, P. et al. 1997. Proc. Natl. Acad. Sci. USA. 94: 2869-2873.
PMID: # 23776567 PLoS ONE. e65915.
PMID: # 21756248 Biosci Rep. 153-60.
PMID: # 22701747 PLoS ONE. e39049.