Anticorps SNX4 (E-2): sc-393853
- L'Anticorps SNX4 (E-2) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 151-450 situés au niveau C-terminus de SNX4 d'origine human
- recommandé pour la détection de SNX4 d'origine mouse, rat et human par WB, IP, IF et ELISA; également réactif avec d'autres espèces, dont equine
- m-IgG Fc BP-HRP, 1 BP-HRP">m-IgG1 BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SNX4 (E-2) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SNX4 (E-2)(voir les informations de commande ci-dessous).
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SNX4 (E-2) | sc-393853 | 200 µg/ml | $316.00 | |||
SNX4 (E-2): m-IgG Fc BP-HRP Kit | sc-538324 | 200 µg Ab; 10 µg BP | $354.00 | |||
SNX4 (E-2): m-IgGκ BP-HRP Kit | sc-535908 | 200 µg Ab; 40 µg BP | $354.00 | |||
SNX4 (E-2): m-IgG1 BP-HRP Kit | sc-545642 | 200 µg Ab; 20 µg BP | $354.00 |