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The sodium-dependent multivitamin transporter (SMVT) is a 635 amino acid protein that belongs to the sodium-coupled glucose transporter family. SMVT contains 12 putative transmembrane domains with the N and C termini both facing towards the cytoplasm. Its function is to transport the essential vitamins pantothenate, biotin, and the metabolite lipoate into cells of various human tissues. Biotin, also known as vitamin B6, is important in synthesizing fatty acids gluconeogenesis, and metabolizing leucine, while pantothenate, or vitamin B5, is critical in the metabolism and synthesis of carbohydrates, proteins, and fats. Lipoate is involved in oxidative metabolism. SMVT uses a specialized carrier-mediated system to take up these vitamins and metabolites into the cells. This process is active and uses energy from the transmembrane sodium ion gradient as well as the membrane potential.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SMVT (C-9) | sc-514319 | 200 µg/ml | $316.00 | |||
SMVT (C-9): m-IgG Fc BP-HRP Kit | sc-538622 | 200 µg Ab; 10 µg BP | $354.00 | |||
SMVT (C-9): m-IgGκ BP-HRP Kit | sc-536268 | 200 µg Ab; 40 µg BP | $354.00 | |||
SMVT (C-9): m-IgG2b BP-HRP Kit | sc-549964 | 200 µg Ab; 10 µg BP | $354.00 | |||
SMVT (C-9) peptide neutralisant | sc-514319 P | 100 µg/0.5 ml | $68.00 |