Anticorps SMS1 (E-5): sc-166436
- L'Anticorps SMS1 (E-5) est un monoclonal de souris IgG2a κ, cité dans 2 publications, fourni en 200 µg/ml
- soulevée à l'encontre des acides aminés 21-150 correspondant à N-terminus de SMS1 d'origine human.
- recommandé pour la détection de SMS1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP, 2a BP-HRP">m-IgG2a BP-HRP et m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps SMS1 (E-5) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps SMS1 (E-5)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The SMS (sphingomyelin synthase) family is a group of integral membrane proteins that includes SMS1 (sphingomyelin synthase 1) and SMS2 (sphingomyelin synthase 2). SMS1 is located in the Golgi apparatus, whereas SMS2 resides primarily at the plasma membrane. Both are bidirectional lipid cholinephosphotransferases which convert phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa, the direction of which depends on the relative concentrations of ceramide and diacylglycerol as phosphocholine acceptors. Therefore, sphingomyelin synthases are thought to be involved in both cell death and survival. Tricyclodecan-9-yl-xanthogenate (D609), a selective tumor cytotoxic agent, inhibits SMS activity, contributing to tumor cell cytotoxicity. SMS proteins are expressed in liver, muscle, heart, brain, stomach and kidney. SMS1 is expressed as four alternatively spliced mRNAs (SMS1α1, SMS1α2, SMS1β and SMS1γ) that translate into three different proteins (SMS1α, SMS1β and SMS1γ), which differ in their tissue distribution and function.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SMS1 (E-5) | sc-166436 | 200 µg/ml | $316.00 | |||
SMS1 (E-5): m-IgG Fc BP-HRP Kit | sc-537488 | 200 µg Ab; 10 µg BP | $354.00 | |||
SMS1 (E-5): m-IgGκ BP-HRP Kit | sc-534767 | 200 µg Ab; 40 µg BP | $354.00 | |||
SMS1 (E-5): m-IgG2a BP-HRP Kit | sc-548028 | 200 µg Ab; 10 µg BP | $354.00 |