Anticorps SMG1 (6-RE13): sc-135563
- L'Anticorps SMG1 (6-RE13) est un monoclonal de souris IgG2a κ, cité dans 5 publications, fourni en 100 µg/ml
- élevé contre la protéine recombinante SMG1 d'origine human.
- recommandé pour la détection de SMG1 d'origine human par WB, IP, IF, IHC(P) et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire SMG1 (6-RE13). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (ser/thr) protein kinases. SMG1, also known as ATX or LIP, is a 3,657 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one FAT domain, one FATC domain, one HEAT repeat and one PI3K domain. Expressed in a variety of tissues, including heart and skeletal muscle, SMG1 functions as a ser/thr protein kinase that uses manganese as a cofactor to catalyze the phosphorylation of target proteins. Via its catalytic activity, SMG1 plays an important role in mRNA surveillance and genotoxic stress-induced response pathways. Multiple isoforms of SMG1 exist due to alternative splicing events.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps SMG1 (6-RE13) | sc-135563 | 100 µg/ml | $333.00 |